FOI Request
- Disclosure ID
- FOI/02678
- Request Date
- September 11, 2018
- Subject
- Surgical Prophylaxis
- Description
- Do you have a policy/guidance for the choice of antibiotics for use peri-operatively as surgical prophylaxis? Yes/No
- Do you have preferred first line agents for use peri-operatively as surgical prophylaxis for implant surgery eg. Orthopaedic Surgery? Yes/No
- If yes: what is/are your first line agent(s) for implant surgery?
- Do you have preferred second line agents for use peri-operatively as surgical prophylaxis where patients have history of penicillin allergy? Yes/No
- If yes: what is/are your second line agent(s) where patients have history of penicillin allergy?
- Do you have preferred agents for use peri-operatively as surgical prophylaxis for patients requiring implants or implantable devices who are MRSA positive or have a history of MRSA? Yes/No
- If yes: what is/are your preferred agent(s)?
- Response
- Yes – See attached document.
- Yes
- ORTHOPAEDIC SURGERY WITH PROSTHESIS – Flucloxacillin 1G IV as a single dose at induction, followed by three further doses of 1G at 6, 12 and 18 hours plus Gentamicin 3MG/KG IV as a single dose at induction.
- Yes
- Mild allergy to penicillins / patients with renal impairment (CrCl < 50mL/min)
Lower doses may be required in patients with severe renal impairment CrCl < 10mL/min
Cefuroxime 1.5g IV as a single dose at induction, followed by two further doses of 750mg at 8 and 16 hours
Serious allergy to penicillins/allergy to cephalosporins/ MRSA colonised or suspected
Teicoplanin 600mg IV as a single dose at induction, followed by one further dose of 600mg at 12 hours PLUS Gentamicin 3mg/kg IV as a single dose at induction
- Yes
- AS 5 PLUS ( IF RENAL IMPAIRMENT)
In patients known to be colonised with MRSA or at high risk of MRSA with renal impairment (CrCl < 50mL/min)
Teicoplanin 600mg IV as a single dose at induction PLUS Cefuroxime 1.5g IV as a single dose at induction