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FOI Request

Disclosure ID
FOI/02678
Request Date
September 11, 2018
Subject
Surgical Prophylaxis
Description
  1. Do you have a policy/guidance for the choice of antibiotics for use peri-operatively as surgical prophylaxis? Yes/No
  2. Do you have preferred first line agents for use peri-operatively as surgical prophylaxis for implant surgery eg. Orthopaedic Surgery? Yes/No
  3. If yes: what is/are your first line agent(s) for implant surgery?
  4. Do you have preferred second line agents for use peri-operatively as surgical prophylaxis where patients have history of penicillin allergy? Yes/No
  5. If yes: what is/are your second line agent(s) where patients have history of penicillin allergy?
  6. Do you have preferred agents for use peri-operatively as surgical prophylaxis for patients requiring implants or implantable devices who are MRSA positive or have a history of MRSA? Yes/No
  7. If yes: what is/are your preferred agent(s)?
Response
  1. Yes – See attached document.
  2. Yes
  3. ORTHOPAEDIC SURGERY WITH PROSTHESIS – Flucloxacillin 1G IV as a single dose at induction, followed by three further doses of 1G at 6, 12 and 18 hours plus Gentamicin 3MG/KG IV as a single dose at induction.
  4. Yes
  5. Mild allergy to penicillins / patients with renal impairment (CrCl < 50mL/min)

    Lower doses may be required in patients with severe renal impairment CrCl < 10mL/min

    Cefuroxime 1.5g IV as a single dose at induction, followed by two further doses of 750mg at 8 and 16 hours

    Serious allergy to penicillins/allergy to cephalosporins/ MRSA colonised or suspected

    Teicoplanin 600mg IV as a single dose at induction, followed by one further dose of 600mg at 12 hours PLUS Gentamicin 3mg/kg IV as a single dose at induction

  6. Yes
  7. AS 5 PLUS ( IF RENAL IMPAIRMENT)

    In patients known to be colonised with MRSA or at high risk of MRSA with renal impairment (CrCl < 50mL/min)

    Teicoplanin 600mg IV as a single dose at induction PLUS Cefuroxime 1.5g IV as a single dose at induction

Attachment 1
corp-guid-309.pdf
Attachment 2
Attachment 3
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Attachment 5
Attachment 6