Eye, Ears, Nose and Throat

Common Pathogen(s)
Usually viruses; Chlamydia

Antibiotic – 1st line
Chloramphenicol 0.5% eye drops 2-hourly until infection controlled, then 6 hourly until 48 hours after healing.

Chlamydia: Doxycycline 100mg q12h PO for 7- 10 days.

Comment
Viral, Chlamydia, and bacterial swabs are required

Antibiotic – 1st line
Co-amoxiclav (consider C difficile risk) 1.2g q8h IV

MRSA colonised, add in Vancomycin IV (dosed as per trust vancomycin guideline)

Comment
Orbital cellulitis is a medical emergency  requiring Ophtho/ Micro input immediately.

Common Pathogen(s)
Strep pneumoniae;
H influenzae.

Antibiotic – 1st line
Amoxicillin 500mg q8h PO for 5 days.

 

2nd Line
Clarithromycin 500mg q12h PO for 5 days

Comment
If mastoiditis, discuss with Microbiologist/ ENT during work hours.

Common Pathogen(s)
Polymicrobial colonisation.

Antibiotic – 1st line
Antibiotics not usually required.

Comment
If malignant otitis externa suspected, discuss with ENT consultant.

Common Pathogen(s)
Strep. Pyogenes.

Antibiotic – 1st line
Phenoxymethyl penicillin 500mg q6h PO and metronidazole 400mg PO q8h
or
Benzylpenicillin 1.2g IV 6 hourly if NBM and metronidazole 500mg IV q8h
if
severe, replace metronidazole with add Clindamycin 600mg q6h IV.

 

Penicillin allergy 
Clindamycin IV 600mg q6h

Comment
If Fusobacterium necroforum (Lemierre’s disease) or oesophageal perforation suspected, discuss with microbiologist

Duration 7 days

Common Pathogen(s)
Commonly – Rhinovirus and other viruses
S. pneumoniae  Haemophilus influenzae
Less common pathogens include: M. catarrhalisS. aureus and anaerobes; fungi are rare pathogens for acute infection.

Antibiotic – 1st line
Amoxicillin  500mg q8h PO

 

Antibiotic – 2nd line
Doxycycline 100mg q 12h PO
Or Clarithromycin 500mg q 12h PO

Comment
Antibacterial should usually be used only for persistent symptoms and purulent discharge lasting at least 7 days or if severe symptoms. Also, consider antibacterial for those at high risk of serious complications (e.g. in immunosuppression, cystic fibrosis).

Duration 5 days

Antibiotic – 1st line
Amoxicillin  500mg q8h PO

 

Antibiotic – 2nd line
Metronidazole 400mg q8h PO

Antibacterial required only in severe disease with cellulitis or if systemic features of infection